AI & Emerging technologies

Associate Principal AI Engineer - Mathematical Optimisation

AstraZeneca

Cambridge · Cambridgeshire · United Kingdom

Overview

In this role you will design, build, and support end-to-end AI and optimisation solutions to tackle complex pharma challenges. You will join a global team to scale analytics across AstraZeneca, driving productivity and impact on patients. You’ll collaborate with engineers, data scientists and scientists to deliver robust, scalable tools and apply state-of-the-art optimisation at scale. This is a hands-on, product-focused engineering role with opportunities to shape how the business operates.

Pay / Benefits
  • Competitive salary
  • Excellent benefits
  • Hybrid work / in-office flexibility
  • Growth and learning opportunities
  • Collaborative culture
  • Inclusive environment
Responsibilities
  • Contribute to design and development of end-to-end AI solutions incorporating mathematical optimisation, modelling and simulation.
  • Visualise complex data and model outputs using modern front-end tech.
  • Collaborate with senior optimisation and AI engineers to deliver through the product lifecycle.
  • Work with colleagues to enhance tech stack and enable adoption of AI and software engineering advances.
  • Contribute to multiple solutions spanning diverse business areas, sometimes concurrently.
  • Be self-driven, curious, innovative, and committed to continuous learning.
Key requirements
  • Experience delivering operations research solutions for real-world problems.
  • Proficiency with mathematical optimisation software (CPLEX, Gurobi, SCIP, OR-Tools).
  • Experience with heuristic and meta-heuristic algorithms.
  • Knowledge of optimisation, simulation, and statistics.
  • Working knowledge of LLM tools.
  • Software development experience using Python and deployment practices (CI/CD, testing, version control).
  • Ability to translate complex business challenges into well-defined engineering problems.
  • Creative
  • Collaborative
  • Product-focused
  • Mathematical optimisation
  • Operations research
  • Heuristic and meta-heuristic algorithms

Reference: WJ-747_31289274 · Posted 11 Nov 2026, 10:26 AM

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